Linked Life Data

6320305

Source:http://linkedlifedata.com/resource/pubmed/id/6320305

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-6
pubmed:dateCreated
1984-3-8
pubmed:abstractText
Bipolar multiple unit recording electrodes were implanted in the striata of male Long-Evans rats 5-7 days prior to experimentation. In subsequent experiments, striatal neuronal activity in response to dexamphetamine (1.0 or 2.5 mg/kg i.p.) was recorded in either freely moving or immobilized, artificially-respired rats. Whereas dexamphetamine produced only excitation of striatal neurons in freely moving animals, a multiplicity of responses, ranging from excitation to inhibition, and including biphasic as well as no change responses were observed in immobilized animals. It is concluded that the absence of dexamphetamine-induced behavior in immobilized animals modifies the striatal neuronal response to dexamphetamine, possibly through alteration of the activity of excitatory striatal afferents.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0278-5846
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
761-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Immobilization-induced changes in the response of striatal neurons to dexamphetamine.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't