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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1984-3-2
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pubmed:abstractText |
Studies of the binding of [3H]-SKF10047 to rat brain membrane preparations revealed a binding site which possessed high affinity for kappa and agonist/antagonist analgesics. However, this site was distinguished from kappa sites labelled with [3H]-ethylketazocine by its high affinity for Met5-enkephalin Arg6.Phe7 and beta-endorphin as well as its low affinity for dynorphin 1-13. We therefore tentatively suggest that this may represent a possible kappa isoreceptor population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Phenazocine,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Opioid,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Opioid, delta,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Opioid, kappa,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Opioid, mu,
http://linkedlifedata.com/resource/pubmed/chemical/SK&F 10047
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pubmed:status |
MEDLINE
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pubmed:issn |
0024-3205
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
33 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
263-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6319874-Animals,
pubmed-meshheading:6319874-Brain,
pubmed-meshheading:6319874-Cell Membrane,
pubmed-meshheading:6319874-Phenazocine,
pubmed-meshheading:6319874-Rats,
pubmed-meshheading:6319874-Receptors, Opioid,
pubmed-meshheading:6319874-Receptors, Opioid, delta,
pubmed-meshheading:6319874-Receptors, Opioid, kappa,
pubmed-meshheading:6319874-Receptors, Opioid, mu
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pubmed:year |
1983
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pubmed:articleTitle |
[3H]-SKF 10047 binding to rat brain membranes: evidence for kappa isoreceptors.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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