Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-3-2
pubmed:abstractText
Good yields of 3H-opioid agonist binding in solution have been obtained following fractionation of brain membrane extracts on sucrose density gradients. The presence of multiple opioid binding sites was demonstrated for extracts from rat and guinea pig brain. Fractionation of solubilized material from guinea pig brain resulted in the separation of the peak of 3H-bremazocine binding (in the presence of DAGO and DADL) from the peaks of binding of tritiated mu and delta agonists. These results suggest that the kappa binding site may represent a separate molecular species from mu and delta opioid binding sites.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0024-3205
pubmed:author
pubmed:issnType
Print
pubmed:volume
33 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-4
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Evidence for the solubilization of multiple opioid binding sites from mammalian brain.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.