Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-3-5
pubmed:abstractText
Cell-free extracts of the Vero cell line (monkey kidney origin) contain an activity which converts 7-[5-[( (1S,4S,5R)-4, 5-dihydroxy-2-cyclopenten-1-yl)-amino]methyl]-7-deazaguanosine (queuosine) 5'-phosphate into queuine (the base of queuosine). We designate this the queuine salvage activity because it apparently is responsible for the ability of intact Vero cells to salvage queuosine base from tRNA degraded during the normal turnover process. Queuosine-3'-P, mannosylqueuosine-5'-P, or queuosine nucleoside does not support the queuine salvage reaction. Extracts of the L-M cell line (mouse embryo origin) lack the queuine salvage activity, a finding consistent with the inability of intact L-M cells to retrieve queuine subsequent to tRNA turnover (Gündüz, U., and Katze, J. R. (1982) Biochem. Biophys. Res. Commun. 109, 159-167).
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0021-9258
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
259
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1110-3
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Queuine salvage in mammalian cells. Evidence that queuine is generated from queuosine 5'-phosphate.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.