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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
5945
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pubmed:dateCreated |
1984-2-14
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pubmed:databankReference |
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pubmed:abstractText |
A cDNA clone corresponding to a mRNA present at elevated levels in transformed fibroblasts encodes a Qa/Tla class I major histocompatibility complex (MHC) antigen. High levels of this mRNA are found in all tumour cells tested; the transcript can undergo alternative splicing; and a repetitive sequence within the transcription unit has the characteristics of a transposable element. The immunological implications of MHC gene activation in tumour cells are discussed.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:issn |
0028-0836
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
306
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
756-60
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6318117-Animals,
pubmed-meshheading:6318117-Antigens, Surface,
pubmed-meshheading:6318117-Base Sequence,
pubmed-meshheading:6318117-Cell Line,
pubmed-meshheading:6318117-Cell Transformation, Viral,
pubmed-meshheading:6318117-DNA Transposable Elements,
pubmed-meshheading:6318117-Gene Expression Regulation,
pubmed-meshheading:6318117-Histocompatibility Antigens Class I,
pubmed-meshheading:6318117-Major Histocompatibility Complex,
pubmed-meshheading:6318117-Mice,
pubmed-meshheading:6318117-RNA Splicing,
pubmed-meshheading:6318117-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:6318117-Teratoma,
pubmed-meshheading:6318117-Transcriptional Activation
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pubmed:articleTitle |
Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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