Linked Life Data

6316717

Source:http://linkedlifedata.com/resource/pubmed/id/6316717

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-1-7
pubmed:abstractText
Acidophilic crystalline inclusion bodies (ACBs) within the cytoplasm of large neurons of the caudate nucleus and putamen were described. ACB was eosinophilic needle-shaped intracytoplasmic material and electronmicroscopically composed of filamentous material. Some were found in the cisterns of rough-surfaced endoplasmic reticulum. There was no histochemical and electronmicroscopic similarity between ACB and Mallory's hyaline bodies of hepatocytes. Though ACBs were noted in a high incidence in alcohol drinkers (65.7%), particularly suffering of alcoholic encephalopathy (72.2%), they were also found in patients without drinking habit (53.9%). In the latter cases, the incidence was high in aged people and patients dying of debilitating diseases (75%) or malignant tumors (57.1%). Consequently, ACB is not pathognomonic for chronic alcoholisms. On histochemical and electron microscopic studies, ACB was considered as a proteinic material, originated from rough-surfaced endoplasmic reticulum, and resulted from some disordered protein synthesis of the neurons.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0001-6632
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
855-61
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Acidophilic crystalline inclusion body in the caudate nerve cells.
pubmed:publicationType
Journal Article