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rdf:type |
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lifeskim:mentions |
umls-concept:C0012854,
umls-concept:C0028630,
umls-concept:C0033268,
umls-concept:C0035366,
umls-concept:C0042776,
umls-concept:C0205088,
umls-concept:C1158478,
umls-concept:C1514873,
umls-concept:C1546857,
umls-concept:C1556066,
umls-concept:C1619636,
umls-concept:C1705422
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pubmed:issue |
5939
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pubmed:dateCreated |
1984-1-7
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pubmed:abstractText |
Deletion of specific nucleotides at either end of the long terminal repeat of the avian retrovirus, spleen necrosis virus, results in replication-competent but integration-defective virus. This result supports two conclusions: (1) the 5-base pair terminal inverted repeats and three to seven adjacent nucleotides are required for integration; (2) integration of retrovirus DNA is not required for retrovirus gene expression.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0028-0836
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
306
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
155-60
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6316141-Cell Nucleus,
pubmed-meshheading:6316141-Cell Transformation, Viral,
pubmed-meshheading:6316141-Chromosome Deletion,
pubmed-meshheading:6316141-Cytoplasm,
pubmed-meshheading:6316141-DNA, Viral,
pubmed-meshheading:6316141-DNA Transposable Elements,
pubmed-meshheading:6316141-Recombination, Genetic,
pubmed-meshheading:6316141-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:6316141-Retroviridae,
pubmed-meshheading:6316141-Virus Replication
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pubmed:articleTitle |
The terminal nucleotides of retrovirus DNA are required for integration but not virus production.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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