Linked Life Data

6315263

Source:http://linkedlifedata.com/resource/pubmed/id/6315263

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-1-27
pubmed:abstractText
Six normal subjects were studied to investigate the mechanisms involved in the release of immunoreactive beta-endorphin (ir-beta EP) in response to insulin hypoglycaemia. Insulin alone (0.2 U/kg body weight) was followed after a 30 min lag period by a congruent to 2.5 fold elevation of plasma ir-beta EP, with a return to basal levels by 90 min. Concurrent infusion of 10% dextrose at 250 ml/h for 2 h prevented the increase in plasma ir-beta EP levels, suggesting an effect of hypoglycaemia rather than a direct effect of insulin. Premedication with atropine 0.6 mg at -30 min was followed by hypoglycaemia equivalent to that seen with insulin alone, but no increase in plasma ir-beta EP, suggesting the involvement of cholinergic mechanisms in the neural mediation of ir-beta EP release in response to hypoglycaemia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0300-0664
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
575-80
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Insulin hypoglycaemia and cholinergic blockade: response of plasma immunoreactive beta-endorphin.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't