Linked Life Data

6315114

Source:http://linkedlifedata.com/resource/pubmed/id/6315114

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-1-7
pubmed:abstractText
Angiotensin converting enzyme activity (ACE), albumin, potassium, and alpha1-antitrypsin were measured in the serum and in the bronchoalveolar lavage fluid (BAL) of 10 normal control subjects and of 19 cases of extrinsic allergic alveolitis (EAA). Among these 19 patients, 6 had a acute form of extrinsic alveolitis, 8 a subacute or chronic form, and 5 received a steroid therapy. Serum ACE is not increased in the acute forms of extrinsic alveolitis, but is significantly lower than control values in the subacute and chronic forms (p less than 0.04) and in patients under steroid therapy (p less than 0.002). The ACE/albumin, ACE/potassium, ACE/IgG and ACE/alpha1-antitrypsin ratios were measured in sera and BAL fluids. The results suggest that ACE is selectively transported across the alveolar capillary septum into the alveolar space. This transport, very important in control subjects, decreases in the subacute and chronic forms and in patients under steroid therapy. In the acute forms, the high level of ACE in BAL fluid is not due to an increased secretion of ACE, but is the result of an increased passive transudation of ACE from the vascular compartment across the inflammatory alveolar capillary septum.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0395-3890
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
439-45
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Angiotensin converting enzyme at different stages of extrinsic allergic alveolitis. Serum and alveolar study].
pubmed:publicationType
Journal Article, English Abstract