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rdf:type |
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lifeskim:mentions |
umls-concept:C0012854,
umls-concept:C0026074,
umls-concept:C0034865,
umls-concept:C0521009,
umls-concept:C0542341,
umls-concept:C0600401,
umls-concept:C0600455,
umls-concept:C0678594,
umls-concept:C1334043,
umls-concept:C1519249,
umls-concept:C2697616
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pubmed:issue |
20
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pubmed:dateCreated |
1983-12-17
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pubmed:abstractText |
Chironomus thummi thummi contains a repetitive AT-rich 118 bp sequence mainly in the centromere regions and elsewhere in the genome (1). A large cluster of repeats is regularly present in the non-transcribed spacer of rDNA. Dimers and multimers of the repeat migrate slower in small pore gels than would be expected from their size. The results indicate a solenoidal structure with a coil girth of appr. 350 bp. This structure is most probably due to a highly periodic positioning of di-nucleotides of the type purine - purine or pyrimidine-pyrimidine with distances of appr. 10 bases. In a cluster of 118 bp repeats, regions of dyad-symmetry are positioned such that a 142 +/- 2 bp palindrome-frame is generated. Evidence is presented favouring the assumption that the repeat functions primarily in sister chromatid exchange.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-1095319,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-1174504,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-119672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-13432333,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-16593261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-277309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-324942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-4128633,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-416935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-4269097,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-4473707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-4517056,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-4778068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-5339944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-5894342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6271563,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6275381,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6290077,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6294479,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6294625,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6296786,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6301779,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6306560,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6306583,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6313353,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6460190,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6777123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6817304,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6933438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6940161,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6987539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-6988084,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-7145714,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-7297251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-7443521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-837802,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6314269-976019
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0305-1048
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6985-96
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pubmed:dateRevised |
2010-9-10
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pubmed:meshHeading |
pubmed-meshheading:6314269-Adenine,
pubmed-meshheading:6314269-Animals,
pubmed-meshheading:6314269-Base Composition,
pubmed-meshheading:6314269-Base Sequence,
pubmed-meshheading:6314269-Chironomidae,
pubmed-meshheading:6314269-Cloning, Molecular,
pubmed-meshheading:6314269-DNA,
pubmed-meshheading:6314269-DNA, Ribosomal,
pubmed-meshheading:6314269-DNA Restriction Enzymes,
pubmed-meshheading:6314269-DNA Transposable Elements,
pubmed-meshheading:6314269-Diptera,
pubmed-meshheading:6314269-Escherichia coli,
pubmed-meshheading:6314269-Plasmids,
pubmed-meshheading:6314269-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:6314269-Thymine
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pubmed:year |
1983
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pubmed:articleTitle |
Structure and function of an AT-rich, interspersed repetitive sequence from Chironomus thummi: solenoidal DNA, 142 bp palindrome-frame and homologies with the sequence for site-specific recombination of bacterial transposons.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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