Linked Life Data

6314043

Source:http://linkedlifedata.com/resource/pubmed/id/6314043

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1983-12-17
pubmed:abstractText
delta-9-tetrahydrocannabinol (THC) and its metabolite, 9-carboxy-THC, were detected in the plasma of a subject during a one-hour passive exposure to the smoke from four marijuana cigarettes containing a total of 104.8 mg of THC. Plasma concentrations of THC were determined by RIA and reached an apparent steady-state concentration of 2.2 ng/mL after 20 minutes of exposure. The presence of THC was confirmed by GC/MS analysis. Results from the two analyses exhibited excellent correlation (r = 0.990), although the concentrations determined by GC/MS were higher than those determined by RIA. Concentrations of 9-carboxy-THC were also determined by GC/MS, and remained consistently below the GC/MS determined concentrations of THC. By administering an infusion of THC, the dose that was inhaled and absorbed during the passive exposure was estimated to be 3.2 micrograms/min.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0146-4760
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
172-4
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Cannabinoid concentrations in plasma after passive inhalation of marijuana smoke.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.