Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-12-20
pubmed:abstractText
The binding of [3H]saxitoxin to a crude membrane fraction from rat brains of various ages was determined. We found that at two days before birth, the maximum number of binding sites is 100 fmol/mg of membrane protein. This value increases rapidly for the two weeks following birth, eventually reaching a plateau value of about 800 fmol of toxin sites per mg protein. Since published reports indicate that rat brain myelination occurs primarily between days 15 and 21, we conclude that the development of sodium channels, as measured by [3H]saxitoxin binding, precedes myelination.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:volume
285
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
405-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Appearance of [3H]saxitoxin binding sites in developing rat brain.
pubmed:publicationType
Journal Article