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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-2
|
| pubmed:dateCreated |
1983-11-23
|
| pubmed:abstractText |
Ranitidine, a new H-2 receptor antagonist more potent than cimetidine in inhibiting gastric secretion, reacted under acid conditions with a twofold molar amount of nitrite (a nitrite/ranitidine ratio about 1000 times that likely to occur in gastric juice of treated humans) yielding a nitroso derivative capable of inducing a dose-dependent DNA fragmentation in cultured Chinese hamster ovary cells.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0378-4274
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
18
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
97-102
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6312641-Animals,
pubmed-meshheading:6312641-Cells, Cultured,
pubmed-meshheading:6312641-Cricetinae,
pubmed-meshheading:6312641-Cricetulus,
pubmed-meshheading:6312641-DNA,
pubmed-meshheading:6312641-Female,
pubmed-meshheading:6312641-Nitroso Compounds,
pubmed-meshheading:6312641-Ranitidine,
pubmed-meshheading:6312641-Stomach
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
DNA damage induced by nitrosated ranitidine in cultured mammalian cells.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|