|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
36
|
|
pubmed:dateCreated |
1983-11-23
|
|
pubmed:abstractText |
Ceftriaxone effectively inhibited 332 out of 452 (73.45%) bacterial strains in vitro tests. 291 out of 365 (79.69%) gram negative and 41 out of 87 (47.12%) gram positive strains were inhibited. The tests showed ceftriaxone to be more effective than cephalothin, cephotaxime, cephuroxime, cephamandol and cephoxitin. Kinetic tests showed that cephtriaxone has a plasmatic half life of 7.25 hrs. 24 hours after administration of a 1000 mg venous bolus the drug was still present in the blood. Urinary elimination over a 24 hr. period amounted to means 486.8 mg (48.68%). The drug has liquor transfer capacity. 37 of the 38 patients treated showed complete clinical or clinicobacteriological cure. Improvement was noted in the 38th.
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|
pubmed:language |
ita
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0026-4806
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:day |
22
|
|
pubmed:volume |
74
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2093-102
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:6312379-Adolescent,
pubmed-meshheading:6312379-Adult,
pubmed-meshheading:6312379-Aged,
pubmed-meshheading:6312379-Cefotaxime,
pubmed-meshheading:6312379-Ceftriaxone,
pubmed-meshheading:6312379-Child,
pubmed-meshheading:6312379-Child, Preschool,
pubmed-meshheading:6312379-Clinical Trials as Topic,
pubmed-meshheading:6312379-Female,
pubmed-meshheading:6312379-Gram-Negative Bacteria,
pubmed-meshheading:6312379-Gram-Positive Bacteria,
pubmed-meshheading:6312379-Half-Life,
pubmed-meshheading:6312379-Humans,
pubmed-meshheading:6312379-Kinetics,
pubmed-meshheading:6312379-Klebsiella Infections,
pubmed-meshheading:6312379-Male,
pubmed-meshheading:6312379-Meningitis,
pubmed-meshheading:6312379-Middle Aged,
pubmed-meshheading:6312379-Respiratory Tract Infections,
pubmed-meshheading:6312379-Staphylococcal Infections,
pubmed-meshheading:6312379-Streptococcal Infections
|
|
pubmed:year |
1983
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|
pubmed:articleTitle |
[Ceftriaxone, a long-acting cephalosporin. Microbiological, kinetic and clinical study].
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|
pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract
|
