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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1983-11-23
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pubmed:abstractText |
The specific activities of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase, EC3.1.4.37) in erythrocyte membranes from five patients with active multiple sclerosis (MS) and five normals were compared. The CNPase assay used 2',3'-cyclic NADP as the substrate in an enzyme coupled reaction to produce fluorometrically detectable NADPH. The specific activity of CNPase in the MS and normal groups were 19.2 +/- 2.3 and 28.7 +/- 1.8 mumol/h/mg protein, respectively. The difference was significant with p less than 0.006, based on a one-tailed t-test.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0277-9382
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-30
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6312248-2',3'-Cyclic-Nucleotide Phosphodiesterases,
pubmed-meshheading:6312248-Adult,
pubmed-meshheading:6312248-Cell Membrane,
pubmed-meshheading:6312248-Erythrocytes,
pubmed-meshheading:6312248-Female,
pubmed-meshheading:6312248-Humans,
pubmed-meshheading:6312248-Male,
pubmed-meshheading:6312248-Middle Aged,
pubmed-meshheading:6312248-Multiple Sclerosis,
pubmed-meshheading:6312248-NADP,
pubmed-meshheading:6312248-Phosphoric Diester Hydrolases
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pubmed:year |
1983
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pubmed:articleTitle |
Erythrocyte membrane 2', 3'-cyclic nucleotide 3'-phosphodiesterase activity in multiple sclerosis.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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