Linked Life Data

6311336

Source:http://linkedlifedata.com/resource/pubmed/id/6311336

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-11-23
pubmed:abstractText
Current intensity thresholds for the detection of electrical brain stimulation were determined from a variety of forebrain and midbrain sites in rats. In a discrete trial, instrumental paradigm, the detection stimulus delivered via one electrode acted as a cue for the availability of response contingent rewarding brain stimulation delivered via a second electrode in the posterolateral hypothalamus. The current intensity of the detection stimulus (20 Hz) was varied according to a modification of the psychophysical method of constant stimuli, while the intensity of contingent rewarding stimulation (160 Hz) was fixed at a highly reinforcing level. Detection thresholds measured from forebrain sites were significantly lower than thresholds from midbrain sites. This difference in detection thresholds was not related to any variability between subjects in site or parameters of the rewarding stimulus used to maintain behavior. Lower detection thresholds from forebrain loci may be due to greater sensitivity to electrical stimuli at the detection site or of the pathways from those sites to areas mediating perception or conditioning.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
272
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
13-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Detection thresholds for electrical stimulation of forebrain and midbrain loci in the rat.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't