pubmed:abstractText |
Blood platelets are a very good model for nerve endings, for study of serotonin uptake and imipramine binding. The efficiency of various drugs, mainly antidepressants, can be evaluated using blood platelets instead of synaptosomes. A few neuronal active compounds are effective in inducing platelet secretion and shape change reaction. Platelet MAO and c-AMP levels are not yet established as useful in psychopharmacological studies.
|