rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
16
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pubmed:dateCreated |
1983-10-8
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pubmed:databankReference |
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pubmed:abstractText |
The complete nucleotide sequence of the genome of the Sabin vaccine strain of poliovirus type 3 (P3/Leon 12 a1 b) has been determined from cDNA cloned in E. coli. The genome comprises a 5' non-coding region of 742 nucleotides, a large open reading frame of 6618 nucleotides (89% of the sequence) and a 3' non-coding region of 72 nucleotides. There is 77.4% base-sequence homology and 89.6% predicted amino-acid homology between types 1 and 3. Conservation of all glutamine-glycine and tyrosine-glycine cleavage sites suggests a mechanism of polyprotein processing similar to that established for poliovirus type 1.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-174102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-189316,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-194650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-196211,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-213732,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-215319,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-225329,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-271968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-4301595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-4340162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-4355536,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6186919,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6246264,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6258294,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6259625,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6260985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6264310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6267593,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6267790,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6272391,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6281371,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6283126,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6283138,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6298715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6298739,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-6310545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-7022155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-7433103,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6310508-787937
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
pubmed:issn |
0305-1048
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
25
|
pubmed:volume |
11
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
5629-43
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6310508-Amino Acid Sequence,
pubmed-meshheading:6310508-Base Sequence,
pubmed-meshheading:6310508-Cloning, Molecular,
pubmed-meshheading:6310508-DNA,
pubmed-meshheading:6310508-Genes,
pubmed-meshheading:6310508-Genes, Viral,
pubmed-meshheading:6310508-Poliovirus,
pubmed-meshheading:6310508-Poliovirus Vaccine, Oral,
pubmed-meshheading:6310508-Species Specificity
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pubmed:year |
1983
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pubmed:articleTitle |
The nucleotide sequence of poliovirus type 3 leon 12 a1b: comparison with poliovirus type 1.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|