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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1983-10-28
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pubmed:abstractText |
Primary cultures of dissociated hypothalamic cells were prepared from 1-day-old rat neonates. Studies with cell-specific antisera revealed the presence of neurons, glial cells, oligodendrocytes and fibroblast-like cells. By immunohistochemistry, two morphologically distinct cells in culture were positive for immunoreactive beta-endorphin (IR-beta-EP). The medium derived from these cultures contained radioimmunoassayable IR-beta-EP, but not IR-ACTH. These data suggest that, in rat neonatal hypothalamic cultures, two subpopulations of cells exist which store and secrete IR-beta-EP, but not IR-ACTH.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0028-3835
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
111-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6310429-Adrenocorticotropic Hormone,
pubmed-meshheading:6310429-Animals,
pubmed-meshheading:6310429-Animals, Newborn,
pubmed-meshheading:6310429-Cells, Cultured,
pubmed-meshheading:6310429-Endorphins,
pubmed-meshheading:6310429-Hypothalamus,
pubmed-meshheading:6310429-Rats,
pubmed-meshheading:6310429-beta-Endorphin
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pubmed:year |
1983
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pubmed:articleTitle |
Neonatal rat hypothalamus cell culture: neuron subpopulations secrete immunoreactive beta-endorphin but not immunoreactive ACTH.
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pubmed:publicationType |
Journal Article,
Comparative Study
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