Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1983-10-21
pubmed:abstractText
The immune response to Japanese encephalitis virus (JEV) was assessed in JEV-infected mice (mothers) and their offspring. The congenitally infected baby mice responded poorly in all assays for cell-mediated immunity. The total number of their splenic cells remained unaltered but the percentage of T cells was significantly reduced; a depressed delayed hypersensitivity response was seen against both homologous (JEV) and heterologous (sheep erythrocytes) antigens. In addition, significantly higher leukocyte migration inhibition (LMI) of spleen cells in the presence of specific antigen was observed. Adult mice infected during pregnancy demonstrated an impaired delayed hypersensitivity response to JEV antigen only. LMI was positive in mothers at 2 weeks post-partum, but not at later periods.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0022-1317
pubmed:author
pubmed:issnType
Print
pubmed:volume
64 (Pt 9)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2027-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Immune response to Japanese Encephalitis virus in mother mice and their congenitally infected offspring.
pubmed:publicationType
Journal Article, Comparative Study