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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1983-9-9
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pubmed:abstractText |
Serum angiotensin-converting enzyme was elevated in patients with hyperthyroidism (72 +/- 31 nmol/minute/ml, n = 12, p less than 0.001) but not in patients with hypothyroidism (38 +/- 3, n = 3) or thyroiditis (26, n = 1), and was positively correlated in 23 patients with serum thyroxine concentration (r = 0.60, p less than 0.01) and triiodothyronine resin uptake (r = 0.56, p less than 0.01). Triiodothyronine failed to enhance the synthesis of angiotensin-converting enzyme in rabbit alveolar macrophages or in human monocytes in culture, suggesting that the increased serum enzyme is a consequence of an effect other than increased angiotensin-converting enzyme synthesis. Hyperthyroidism should be considered in the evaluation of serum angiotensin-converting enzyme for the diagnosis and management of sarcoidosis.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0002-9343
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
233-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6309003-Dexamethasone,
pubmed-meshheading:6309003-Humans,
pubmed-meshheading:6309003-Hyperthyroidism,
pubmed-meshheading:6309003-Hypothyroidism,
pubmed-meshheading:6309003-Macrophages,
pubmed-meshheading:6309003-Monocytes,
pubmed-meshheading:6309003-Peptidyl-Dipeptidase A,
pubmed-meshheading:6309003-Thyroiditis,
pubmed-meshheading:6309003-Thyroxine,
pubmed-meshheading:6309003-Triiodothyronine
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pubmed:year |
1983
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pubmed:articleTitle |
Elevated serum angiotensin-converting enzyme in hyperthyroidism.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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