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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1983-8-26
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pubmed:abstractText |
The mononuclear cell infiltrate in benign and malignant breast tissue was studied using monoclonal antibodies with an immunoenzymatic technique. Infiltrating duct carcinomas contained a mononuclear cell infiltrate made up mostly of T lymphocytes, with minor B-cell and macrophage populations. The most preponderant T-cell subset was the T8, cytotoxic-suppressor cell. Some tumors contained T6-positive cells, possibly immature T cells. In contrast, stromal lymphocytes in benign fibrous mastopathy were largely T cells, but the T4, helper-inducer cell was the most preponderant, and T6 cells were not detected. Intraepithelial lymphocytes were identified in benign breast tissue. Intraepithelial lymphocytes are T cells, with a great preponderance of the T8 phenotype. The T6-positive cells were also identified within the epithelium, but they seemed to represent myoepithelial cells rather than immature T cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0003-9985
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
415-7
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:6307213-Antibodies, Monoclonal,
pubmed-meshheading:6307213-B-Lymphocytes,
pubmed-meshheading:6307213-Breast,
pubmed-meshheading:6307213-Breast Neoplasms,
pubmed-meshheading:6307213-Carcinoma, Intraductal, Noninfiltrating,
pubmed-meshheading:6307213-Female,
pubmed-meshheading:6307213-Fibrocystic Breast Disease,
pubmed-meshheading:6307213-Humans,
pubmed-meshheading:6307213-Macrophages,
pubmed-meshheading:6307213-T-Lymphocytes,
pubmed-meshheading:6307213-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:6307213-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:6307213-T-Lymphocytes, Regulatory
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pubmed:year |
1983
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pubmed:articleTitle |
Mononuclear cells in malignant and benign human breast tissue.
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pubmed:publicationType |
Journal Article
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