rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1983-7-29
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pubmed:abstractText |
1. Measurements were made of the maximal low-density lipoprotein (LDL) receptor activities of blood lymphocytes from 81 healthy men with a wide range of plasma LDL cholesterol concentrations (1.45-7.55 mmol/l). 2. Receptor activity was quantified by measuring the degradation of 125I-labelled LDL (10 micrograms of protein/ml) to trichloroacetic acid-soluble material during a 6 h incubation, after derepression of the lymphocytes for 72 h in lipoprotein-deficient medium. 3. No significant correlation existed between LDL receptor activity in vitro and plasma LDL cholesterol concentration in vivo (r = -0.08).
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, VLDL,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, LDL
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0143-5221
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6303675-Adult,
pubmed-meshheading:6303675-Cholesterol,
pubmed-meshheading:6303675-Cholesterol, LDL,
pubmed-meshheading:6303675-Humans,
pubmed-meshheading:6303675-Lipoproteins, HDL,
pubmed-meshheading:6303675-Lipoproteins, LDL,
pubmed-meshheading:6303675-Lipoproteins, VLDL,
pubmed-meshheading:6303675-Lymphocytes,
pubmed-meshheading:6303675-Male,
pubmed-meshheading:6303675-Middle Aged,
pubmed-meshheading:6303675-Receptors, Cell Surface,
pubmed-meshheading:6303675-Receptors, LDL
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pubmed:year |
1983
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pubmed:articleTitle |
Lack of correlation between the maximum low-density lipoprotein (LDL) receptor activity of blood lymphocytes and plasma LDL concentration in normal men.
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pubmed:publicationType |
Journal Article
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