Linked Life Data

6302637

Source:http://linkedlifedata.com/resource/pubmed/id/6302637

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-6-10
pubmed:abstractText
The activation time course of the pacemaker current if in Purkinje fibres during hyperpolarizations is s-shaped, which requires kinetics more complex than first order. Large, short hyperpolarizations preceding a fixed activating test pulse cause the current trace to shift to the left on the time-axis, as if a delay in if activation were removed, and eventually lead to a current trace which is a simple exponential and activates with no delay during a test pulse. Current traces before and after a relatively short and small prepulse will superimpose after a time translation. Further increasing prepulse amplitude and/or duration gives current traces that cannot be made to superimpose with the test current trace. The channel opening can be described by first order kinetics only if a delay in current activation is introduced.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0031-6768
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
396
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
265-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Delayed activation of the cardiac pacemaker current and its dependence on conditioning pre-hyperpolarizations.
pubmed:publicationType
Journal Article