Linked Life Data

6301203

Source:http://linkedlifedata.com/resource/pubmed/id/6301203

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-5-27
pubmed:abstractText
An experimental diabetic state was induced in rats by means of an injection of streptozotocin. A histological and histometric evaluation of randomly teased nerve fibers was applied to the common peroneal nerves of both diabetic and age- and weight-matched control rats. A long-term (6-12 months) exposure to the diabetic state was required for the demonstration of the following morphological changes: (1) splitting and notching of myelin sheaths, (2) decrease in the ratio of internodal length/internodal diameter, (3) widening of nodal gaps. This study showed that neurons of smaller caliber are preferentially affected after a prolonged period of the diabetic condition. Neurons of this size are representative of sensory and autonomic components, suggesting that the changes present in this model parallel the derangements of these constituents reported in the human diabetic with adult onset disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6322
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-8
pubmed:dateRevised
2007-11-9
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Peripheral neuropathy following prolonged exposure to streptozotocin-induced diabetes in rats: a teased nerve fiber study.
pubmed:publicationType
Journal Article