Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1983-5-27
pubmed:abstractText
Using monoclonal antibodies, we demonstrate that the phosphoprotein of measles virus and a protein of herpes simplex virus type 1 crossreact with an intermediate filament protein of human cells. This intermediate filament protein, probably vimentin, has a molecular weight of 52,000, whereas the molecular weights of the measles viral phosphoprotein and the herpes virus protein are 70,000 and 146,000, respectively. Crossreactivity was shown by immunofluorescent staining of infected and uninfected cells and by immunoblotting. The monoclonal antibody against measles virus phosphoprotein did not react with herpes simplex virus protein and vice versa, indicating that these monoclonal antibodies recognize different antigenic determinants on the intermediate filament molecule. The significance of these results in explaining the appearance of autoantibodies during virus infections in humans is discussed.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-200698, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-202655, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-224538, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-268647, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-305001, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-365400, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-385189, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-388439, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-389499, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-4290961, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-4323748, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-4566024, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-499577, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6086105, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6115318, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6167634, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6174868, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6176652, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6177775, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6178950, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6179699, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6245226, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6252336, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6257787, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6265586, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6267791, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6751555, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6804567, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6895382, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-6997994, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-7063025, http://linkedlifedata.com/resource/pubmed/commentcorrection/6300911-7129626
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2346-50
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Molecular mimicry in virus infection: crossreaction of measles virus phosphoprotein or of herpes simplex virus protein with human intermediate filaments.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't