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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1983-5-5
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pubmed:abstractText |
The host nuclear enzyme poly(ADP-ribose) polymerase has been shown to be associated with the replicative intermediate and mature forms of polyoma virus minichromosomes. Minichromosome-associated histones H2A and H2B as well as several nonhistone proteins were poly ADP-ribosylated by endogenous poly(ADP-ribose) polymerase. In addition, minichromosome fractions catalyzed the formation in vitro of dimers of endogenous histone H1 linked by poly(ADP-ribose). Poly ADP-ribosylated polyoma virus minichromosome chromatin labeled in vivo with [3H]thymidine could be retained and eluted from anti-poly(ADP-ribose) immunoglobulin G-Sepharose. Pulse-labeled replicative intermediate minichromosomes were retained better on the antibody columns than were mature minichromosomes labeled for 2.5 h. The possible role of poly ADP-ribosylation of viral nucleosomes during polyoma replication or transcription is discussed.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-163367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-169064,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-184438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-197884,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-202502,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-209938,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-217534,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-4343541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-4349570,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-4356978,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-447840,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-500667,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-526299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-5778650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-5840387,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-590272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-6243744,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-6253084,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-6253477,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-6264155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-6264156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-6264157,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-6300422,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-643606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-666823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-6766739,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-7237559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-7448164,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-7448165,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6300423-7460942
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
600-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6300423-Chromatin,
pubmed-meshheading:6300423-Chromatography, Affinity,
pubmed-meshheading:6300423-Chromosomal Proteins, Non-Histone,
pubmed-meshheading:6300423-Histones,
pubmed-meshheading:6300423-NAD+ Nucleosidase,
pubmed-meshheading:6300423-Nucleoside Diphosphate Sugars,
pubmed-meshheading:6300423-Poly(ADP-ribose) Polymerases,
pubmed-meshheading:6300423-Poly Adenosine Diphosphate Ribose,
pubmed-meshheading:6300423-Polyomavirus,
pubmed-meshheading:6300423-Virus Replication
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pubmed:year |
1983
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pubmed:articleTitle |
Polyoma virus minichromosomes: poly ADP-ribosylation of associated chromatin proteins.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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