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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1978-4-26
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pubmed:abstractText |
The overall, static, open-loop gain of the negative-feedback arterial pressure control system was determined repeatedly in anesthetized cats under normal and hypovolumic states. The gain, H, was assessed as (deltaAPI/deltaAPS)-1, where deltaAPI is the immediate fall and deltaAPS the steady-state fall in arterial pressure following a stepwise reduction in blood volume. When the step size was increased from 1.25 to 25% of the total blood volume, H decreased from 30 to less than unity. Considering this amplitude dependence of H, a small amount (1.25%) of quick (in less than 0.3 s) hemorrhage was used to determine H throughout the rest of the experiments. Time-dependent variation of H was evident after a large amount (6.25%) of blood loss. During the initial 10 min, H increased to 126% of the control value, decreased to 43% over the subsequent 20--70 min, and showed a trend toward recovery. The small signal analysis permits a quantitative characterization of the time and input size dependent nature of the arterial pressure control system after various degrees of hemorrhage.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0002-9513
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
234
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
R104-9
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:629366-Animals,
pubmed-meshheading:629366-Blood Pressure,
pubmed-meshheading:629366-Blood Volume,
pubmed-meshheading:629366-Cats,
pubmed-meshheading:629366-Feedback,
pubmed-meshheading:629366-Female,
pubmed-meshheading:629366-Hemorrhage,
pubmed-meshheading:629366-Male,
pubmed-meshheading:629366-Pressoreceptors
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pubmed:year |
1978
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pubmed:articleTitle |
Overall characteristics of arterial pressure control system studied by mild hemorrhage.
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pubmed:publicationType |
Journal Article
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