Linked Life Data

629348

Source:http://linkedlifedata.com/resource/pubmed/id/629348

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1978-4-26
pubmed:abstractText
A procedure is described for the setting up of a preparation of mammalian gastric mucosa from kitten or ferret. The mucosa is stripped of its outer muscle coats except for a 2-mm strip of circular muscle fibers running across the diameter of the preparation. The connections of this strip to the underlying mucosa are undisturbed. The preparation is immersed on the nutrient side in Krebs-Henseleit solution, gassed with 95% O2 and 5% CO2, and the secretory side contains 5% dextrose, both at 37 degrees C. Acid secretion is determined by a pH stat method and motility is recorded by a strain gauge attached to one end of the muscle strip. Secretory and motility responses are recorded for the three main parietal cell agonists, acetylcholine (ACh), pentagastrin, and histamine. In all cases, concentrations adequate to produce secretory effects also produced modulation of motor activity. In both animals the similarity between the motility responses produced by cholinergic stimulation and pentagastrin was notable.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
234
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
E319-26
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Acid secretion and motility of isolated mammalian gastric mucosa and attached muscularis externa.
pubmed:publicationType
Journal Article