| pubmed-article:6293295 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C0006684 | lld:lifeskim |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C0086907 | lld:lifeskim |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C0028066 | lld:lifeskim |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C0005823 | lld:lifeskim |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C0232117 | lld:lifeskim |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C0085580 | lld:lifeskim |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:6293295 | lifeskim:mentions | umls-concept:C0949236 | lld:lifeskim |
| pubmed-article:6293295 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:6293295 | pubmed:dateCreated | 1983-1-7 | lld:pubmed |
| pubmed-article:6293295 | pubmed:abstractText | Ten milligrams nifedipine was administered orally to young and old persons with or without hypertension, and the acute effects of nifedipine on the renin-angiotensin-aldosterone system were studied one half to 3 hours later. Nifedipine reduced blood pressure and increased pulse rate in young and old persons with or without hypertension. Simultaneously, nifedipine produced a significant increase of plasma renin activity in young persons with or without hypertension but failed to do so in old persons with or without hypertension. As a result, angiotensin I and II increased significantly in young persons but not in old persons. Hydralazine elevated aldosterone concentration by stimulating the renin-angiotensin system but nifedipine failed to do so despite its effect on the renin-angiotensin system in young individuals. Since calcium is required to secrete aldosterone, it is suggested that nifedipine blocked aldosterone secretion by the agent's calcium antagonizing action. | lld:pubmed |
| pubmed-article:6293295 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6293295 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293295 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:6293295 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293295 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293295 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293295 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293295 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293295 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293295 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:6293295 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6293295 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6293295 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:6293295 | pubmed:issn | 0002-8703 | lld:pubmed |
| pubmed-article:6293295 | pubmed:author | pubmed-author:YamadaTT | lld:pubmed |
| pubmed-article:6293295 | pubmed:author | pubmed-author:KubotaTT | lld:pubmed |
| pubmed-article:6293295 | pubmed:author | pubmed-author:HiramatsuKK | lld:pubmed |
| pubmed-article:6293295 | pubmed:author | pubmed-author:YamagishiFF | lld:pubmed |
| pubmed-article:6293295 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6293295 | pubmed:volume | 104 | lld:pubmed |
| pubmed-article:6293295 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6293295 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6293295 | pubmed:pagination | 1346-50 | lld:pubmed |
| pubmed-article:6293295 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:6293295 | pubmed:meshHeading | pubmed-meshheading:6293295-... | lld:pubmed |
| pubmed-article:6293295 | pubmed:year | 1982 | lld:pubmed |
| pubmed-article:6293295 | pubmed:articleTitle | Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension. | lld:pubmed |
| pubmed-article:6293295 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6293295 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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