Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1978-4-26
pubmed:abstractText
Catheters were placed in maternal and fetal vessels in four ewes in the last month of gestation. Tritiated progesterone (P) was infused at a constant rate into a maternal peripheral vein. Specific activities and endogenous concentrations of P were measured in blood samples drawn from a maternal artery and either a fetal femoral artery or an umbilical vein. Comparison of the specific activities of P in fetal and maternal samples revealed that direct secretion of the placental hormone into the umbilical vein accounted for 90 to 93 per cent of the hormone in the fetal circulation. Estimates of the rates of production of P in the fetal circulation, obtained by multiplying metabolic clearance rates previously reported and concentrations of P in a fetal femoral artery, indicate that placental P is preferentially secreted toward the maternal circulation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0002-9378
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
130
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
466-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Contribution of maternal circulation to blood-borne progesterone in the fetus. II. Studies on sheep.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.