Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1983-1-19
|
pubmed:abstractText |
The course of coxsackievirus B4 necrotizing myocarditis was studied over a 12-month period in 712 ICR Swiss mice inoculated at less than 48 h of age. Affected animals were sacrificed at intervals until 1 year. Microscopically, focal myocardial necrosis, which was often transmural in extent with mixed inflammatory exudate, and subsequent fibrous replacement were induced in 75% of the examined animals. The left ventricle (63 of 69 subjects, 91.3%), interventricular septum (39 of 69 subjects, 56.5%) and right ventricle (26 of 69 subjects, 37.7%) were most frequently involved. Thinning of the ventricular wall and grossly apparent localized ventricular bulges (aneurysms) were seen in 22 subjects (the left ventricle 16 times, the right ventricle 5 times, and the interventricular septum 5 times). Coronary arteries were normal in all instances.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-5526
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
197-202
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6292132-Animals,
pubmed-meshheading:6292132-Antigens, Viral,
pubmed-meshheading:6292132-Disease Models, Animal,
pubmed-meshheading:6292132-Enterovirus B, Human,
pubmed-meshheading:6292132-Mice,
pubmed-meshheading:6292132-Myocarditis,
pubmed-meshheading:6292132-Necrosis,
pubmed-meshheading:6292132-Time Factors
|
pubmed:year |
1982
|
pubmed:articleTitle |
A mouse model of transmural myocardial necrosis due to coxsackievirus B4: observations over 12 months.
|
pubmed:publicationType |
Journal Article
|