Linked Life Data

6291115

Source:http://linkedlifedata.com/resource/pubmed/id/6291115

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-12-16
pubmed:abstractText
A closed chest model in mechanically ventilated dogs is presented for the study of electromechanical dissociation (EMD) after defibrillation for ventricular fibrillation (VF). In seven dogs VF was induced by internal application of an AC current in the right ventricle. Precordial compression was not performed. When VF was continued for either 30 s or 60 s defibrillation typically resulted in complete restoration of electrical and mechanical cardiac activity. Immediately after defibrillation, the mean arterial blood pressure, pulmonary artery pressure, right ventricular filling pressure and cardiac output were markedly elevated; these elevations were accompanied by a slight increase in lactate and a decline in pH of the arterial blood. When VF was continued for 120 s EMD was observed in each instance after defibrillation in association with a regular rhythm. After 5-20 min, the ventricular fibrillation reappeared. The constancy of EMD in this model provides an experimental basis for study of clinical options, by which EMD may be prevented and/or mechanical competence of the heart may be restored.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0300-9572
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
25-32
pubmed:dateRevised
2009-8-25
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
A closed-chest model for the study of electromechanical dissociation of the heart in dogs.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't