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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1982-12-21
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pubmed:abstractText |
An inhibitor of protein synthesis was activated under high oxygen partial pressure (pO2) in hemin-supplemented and glutathione disulfide-free lysates from rabbit reticulocytes. This inhibitor shared some common features with other translational inhibitors from rabbit reticulocytes; that is, hemin-controlled repressor, glutathione disulfide-activated inhibitor and high pressure-activated inhibitor. It caused biphasic kinetics of inhibition which could be potentiated by ATP. Its activation was prevented by cAMP or glucose 6-phosphate. The high pO2-inhibitor could be partially purified from post-ribosomal supernatant containing ribosomal salt wash by precipitation between 0-50% (NH4)2SO4-saturation, Sephadex G-100, and DEAE-cellulose chromatography.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
16
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
143-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6290264-Animals,
pubmed-meshheading:6290264-Chromatography, Gel,
pubmed-meshheading:6290264-Cyclic AMP,
pubmed-meshheading:6290264-Glucosephosphates,
pubmed-meshheading:6290264-Glutathione,
pubmed-meshheading:6290264-Oxygen,
pubmed-meshheading:6290264-Protein Biosynthesis,
pubmed-meshheading:6290264-Rabbits,
pubmed-meshheading:6290264-Reticulocytes
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pubmed:year |
1982
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pubmed:articleTitle |
A translational inhibitor activated in rabbit reticulocyte lysates under high pO2.
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pubmed:publicationType |
Journal Article
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