Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7994
|
pubmed:dateCreated |
1977-1-25
|
pubmed:abstractText |
30 families in which at least one member has asthma were tested for five new specificities of B lymphocytes as well as for twenty-five HLA antigens. 41 other asthmatic patients were also tested. HLA-B8 was slightly less common than normal in the 71 patients with asthma and there was a trend towards an increased frequency of HLA-A2 in these patients. However, 88% of the 30 asthma patients had B lymphocyte group 2 compared with 24% of the 109 controls. This strong association between asthma and B lymphocyte group 2 was not completely paralleled by linkage with a postulated susceptibility gene of the HLA complex in 9 families whose members were investigated in detail.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0140-6736
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
13
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1042-4
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:62898-Adult,
pubmed-meshheading:62898-Alleles,
pubmed-meshheading:62898-Asthma,
pubmed-meshheading:62898-B-Lymphocytes,
pubmed-meshheading:62898-Child,
pubmed-meshheading:62898-Epitopes,
pubmed-meshheading:62898-Female,
pubmed-meshheading:62898-Genetic Linkage,
pubmed-meshheading:62898-HLA Antigens,
pubmed-meshheading:62898-Haploidy,
pubmed-meshheading:62898-Histocompatibility Antigens,
pubmed-meshheading:62898-Humans,
pubmed-meshheading:62898-Male
|
pubmed:year |
1976
|
pubmed:articleTitle |
Strong association between B-lymphocyte group-2 specificity and asthma.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|