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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4570
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pubmed:dateCreated |
1982-12-3
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pubmed:databankReference |
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pubmed:abstractText |
The protein coding region of the herpes simplex virus type-1 glycoprotein D (gD) gene was mapped, and the nucleotide sequence was determined. The predicted amino acid sequence of the gD polypeptide was found to contain a number of features in common with other virus glycoproteins. Insertion of this protein coding region into a bacterial expressor plasmid enabled synthesis in Escherichia coli of an immunoreactive gD-related polypeptide. The potential of this system for preparation of a type-common herpes simplex virus vaccine is discussed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0036-8075
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
22
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pubmed:volume |
218
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
381-4
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:6289440-Amino Acid Sequence,
pubmed-meshheading:6289440-Antigens, Viral,
pubmed-meshheading:6289440-Base Sequence,
pubmed-meshheading:6289440-Escherichia coli,
pubmed-meshheading:6289440-Gene Expression Regulation,
pubmed-meshheading:6289440-Genes,
pubmed-meshheading:6289440-Genes, Viral,
pubmed-meshheading:6289440-Glycoproteins,
pubmed-meshheading:6289440-Peptides,
pubmed-meshheading:6289440-Protein Sorting Signals,
pubmed-meshheading:6289440-Simplexvirus,
pubmed-meshheading:6289440-Viral Proteins,
pubmed-meshheading:6289440-Viral Vaccines
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pubmed:year |
1982
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pubmed:articleTitle |
Herpes simplex virus type-1 glycoprotein D gene: nucleotide sequence and expression in Escherichia coli.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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