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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1982-12-3
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pubmed:abstractText |
Fourteen previously untreated patients with metastatic nonseminomatous germ cell cancer of the testis (NSGC) were treated with a modified VAB-4 regimen which was designed to reduce treatment-related morbidity. Nine of 10 patients with minimal disease and the only patient with advanced pulmonary disease achieved a complete response (CR) with chemotherapy alone. Two of three partial responders with advanced abdominal disease were converted to CR status with radiotherapy and/or surgery. None of the 12 CRs have relapsed (median duration of follow-up, 28+ months). We observed no granulocytopenic fever or permanent renal insufficiency. These results indicate that NSGC patients with a low tumor burden can be spared substantial toxicity without adversely affecting complete response rates.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
|
pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1742-5
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6288223-Antineoplastic Agents,
pubmed-meshheading:6288223-Drug Administration Schedule,
pubmed-meshheading:6288223-Drug Therapy, Combination,
pubmed-meshheading:6288223-Humans,
pubmed-meshheading:6288223-Leukopenia,
pubmed-meshheading:6288223-Male,
pubmed-meshheading:6288223-Neoplasm Metastasis,
pubmed-meshheading:6288223-Neoplasm Staging,
pubmed-meshheading:6288223-Neoplasms, Germ Cell and Embryonal,
pubmed-meshheading:6288223-Prognosis,
pubmed-meshheading:6288223-Testicular Neoplasms
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pubmed:year |
1982
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pubmed:articleTitle |
Nonseminomatous germ cell cancer of the testis. Reducing treatment-related morbidity in patients with disseminated disease.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
|