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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1982-9-10
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pubmed:abstractText |
A batch of 417 serum samples obtained from native-born subjects were tested for the presence of hepatitis B surface antigen (HBsAg) and corresponding antibody (anti-HBs), by enzyme-linked immunosorbent assay (ELISA); and antibodies to hepatitis B core antigen (anti-HBc), e-antigen (anti-HBe), and hepatitis A virus (anti-HAV), by radioimmunoassay (RIA). HBsAg was found in only two of the 417 subjects studied. Anti-HBs was detected in 112 samples (26.8%), anti-HBc in 114 (27.3%) and anti-HBe in 31 samples (7.4%). Serologic evidence of a previous or present infection by hepatitis B virus (HBV) was found in 34.5% of the samples studied. Males showed a greater prevalence of anti-HBs and anti-HBc, while anti-HBe was more common in females; however, these differences were not significant. With regard to age, a significantly higher prevalence of anti-HBs (p less than 0.05), anti-HBc (p less than 0.025) and anti-HBe (p less than 0.025) was found in the older age groups. Anti-HAV antibodies were present in 90% of the subjects studied, with no variation between the sexes. The anti-HAV rate in the group under 20 years was similar to that found in the older age groups. The total infection rate of hepatitis B virus in the Seychelles is lower than in other tropical areas, HBs antigen/antibody ratio approaching that in temperate areas. Elucidation of the reasons for the low prevalence of hepatitis B virus carriers among the Sevchelles population requires further investigation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0002-9262
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6285695-Adolescent,
pubmed-meshheading:6285695-Adult,
pubmed-meshheading:6285695-Antibodies, Viral,
pubmed-meshheading:6285695-Child,
pubmed-meshheading:6285695-Epidemiologic Methods,
pubmed-meshheading:6285695-Female,
pubmed-meshheading:6285695-Hepatitis A,
pubmed-meshheading:6285695-Hepatitis B,
pubmed-meshheading:6285695-Hepatitis B Antibodies,
pubmed-meshheading:6285695-Hepatitis B Surface Antigens,
pubmed-meshheading:6285695-Hepatovirus,
pubmed-meshheading:6285695-Humans,
pubmed-meshheading:6285695-Male,
pubmed-meshheading:6285695-Middle Aged,
pubmed-meshheading:6285695-Seychelles
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pubmed:year |
1982
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pubmed:articleTitle |
Seroepidemiology of infection with hepatitis A virus and hepatitis B virus in the Seychelles.
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pubmed:publicationType |
Journal Article
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