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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4557
|
pubmed:dateCreated |
1982-8-26
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pubmed:databankReference | |
pubmed:abstractText |
Transcriptional control signals of a model eukaryotic protein-coding gene have been identified by a new procedure of in vitro mutagenesis. This method allows small clusters of nucleotide residues to be substituted in a site-directed manner without causing the addition or deletion of other sequences. Transcription assays of a systematic series of these clustered point mutants have led to the identification of three distinct control signals located within the 105-nucleotide residues immediately upstream from the point where transcription begins.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
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pubmed:issn |
0036-8075
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
23
|
pubmed:volume |
217
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
316-24
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:6283634-Base Sequence,
pubmed-meshheading:6283634-DNA, Recombinant,
pubmed-meshheading:6283634-Gene Expression Regulation,
pubmed-meshheading:6283634-Genes,
pubmed-meshheading:6283634-Genes, Regulator,
pubmed-meshheading:6283634-Mutation,
pubmed-meshheading:6283634-RNA, Messenger,
pubmed-meshheading:6283634-Simplexvirus,
pubmed-meshheading:6283634-Thymidine Kinase,
pubmed-meshheading:6283634-Transcription, Genetic
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pubmed:year |
1982
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pubmed:articleTitle |
Transcriptional control signals of a eukaryotic protein-coding gene.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|