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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1982-8-26
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pubmed:abstractText |
The beta-adrenergic hormone responsiveness of mouse epidermis exhibited an age-dependent decrease. The 3-4-fold loss of response to isoproterenol was seen between 3 and 6 months of age, and the response remained at a depressed level through 18 months of age. No differences were seen between either the number or binding affinities of epidermal beta-receptors in 2- and 12-month-old animals. The skin tumor promoter, phorbol myristate acetate, inhibited the beta-adrenergic response independently of age.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
pubmed:issn |
0047-6374
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
209-14
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6283278-Aging,
pubmed-meshheading:6283278-Animals,
pubmed-meshheading:6283278-Cyclic AMP,
pubmed-meshheading:6283278-Epidermis,
pubmed-meshheading:6283278-Female,
pubmed-meshheading:6283278-Isoproterenol,
pubmed-meshheading:6283278-Mice,
pubmed-meshheading:6283278-Mice, Inbred ICR,
pubmed-meshheading:6283278-Phorbols,
pubmed-meshheading:6283278-Tetradecanoylphorbol Acetate
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pubmed:year |
1982
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pubmed:articleTitle |
Comparison of the effects of age and phorbol myristate acetate on the beta-adrenergic system in mouse epidermis.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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