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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1982-7-8
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pubmed:abstractText |
Transferrin receptor activity has been investigated on isolated human placental syncytiotrophoblast microvillous plasma membrane preparations following 3 M KCl washing of membranes to remove endogenous receptor-bound maternal transferrin. The calculated binding parameters for essentially apo- and diferric human transferrin, and also for rabbit transferrin, were closely comparable (ranges: Ka, 3.5 to 5.0 X 10(7) M-1; n, 2.6 to 4.0 X 10(14)/mg membrane protein). Iron transport in pregnancy is thus unlikely to involve a simple process of transferrin displacement following iron release at the placental trophoblast plasma membrane receptor site.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0143-4004
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
21-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6281752-Biological Transport,
pubmed-meshheading:6281752-Female,
pubmed-meshheading:6281752-Humans,
pubmed-meshheading:6281752-Iron,
pubmed-meshheading:6281752-Maternal-Fetal Exchange,
pubmed-meshheading:6281752-Placenta,
pubmed-meshheading:6281752-Pregnancy,
pubmed-meshheading:6281752-Receptors, Cell Surface,
pubmed-meshheading:6281752-Receptors, Transferrin
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pubmed:articleTitle |
Transferrin receptor affinity and iron transport in the human placenta.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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