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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1982-7-22
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pubmed:abstractText |
The mouse hepatitis virus strain A59 codes for seven RNA species in the infected cells. These virus-specific RNAs were found to be polysome associated and therefore likely to represent mRNA's. All of them have common 3'-end sequences (Lai et al., J. Virol. 39:823-834, 1981). Their structure was further studied with respect to their 5'-end sequences. It was found that all of these mRNA's contained cap structures at their 5' ends. Furthermore, the cap-containing oligonucleotides which represent the sequences immediately adjacent to the 5' ends were found to be the same for most, if not all, of the seven virus-specific mRNA's. These sequences are also identical to the 5'-end sequences of the virion RNA genome. The 5'-end sequences were tentatively determined to be 5'-cap-N-UAAG. The presence of the common nucleotides in all of the virus-specific RNAs in mouse hepatitis virus strain A59 suggests several possible mechanisms of synthesis for these RNAs. The significance of these findings is discussed.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-199998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-200604,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-207885,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-214517,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-224595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-228084,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-572113,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-6165837,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-6169842,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-6171615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-6258295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-6259831,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-6262335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-6264100,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-6268831,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-7276911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-7281517,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-729003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-7365865,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6281467-855186
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
557-65
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1982
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pubmed:articleTitle |
Further characterization of mRNA's of mouse hepatitis virus: presence of common 5'-end nucleotides.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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