6280605

Source:http://linkedlifedata.com/resource/pubmed/id/6280605

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001367, umls-concept:C0013227, umls-concept:C0282443, umls-concept:C1516606, umls-concept:C1552617, umls-concept:C1709630
pubmed:issue	4
pubmed:dateCreated	1982-6-21
pubmed:abstractText	A review of the literature on acyclovir (Zovirax), a new antiherpes drug, with particular activity against herpes simplex virus types I and II and also against varicella-zoster, Epstein-Barr, cytomegalo and herpes B viruses, is presented. The article deals with 'in vitro' and 'in vivo' efficacy in animals, animal toxicity, latency and resistance, the mechanism of action and early clinical experience.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8109699
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Acyclovir, http://linkedlifedata.com/resource/pubmed/chemical/Guanine
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	0166-3542
pubmed:author	pubmed-author:BrigdenDD, pubmed-author:FiddianPP, pubmed-author:RavenscroftTT, pubmed-author:RoslingA EAE
pubmed:issnType	Print
pubmed:volume	1
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	203-12
pubmed:dateRevised	2007-11-15
pubmed:meshHeading	pubmed-meshheading:6280605-Acyclovir, pubmed-meshheading:6280605-Animals, pubmed-meshheading:6280605-Clinical Trials as Topic, pubmed-meshheading:6280605-Drug Resistance, Microbial, pubmed-meshheading:6280605-Guanine, pubmed-meshheading:6280605-Guinea Pigs, pubmed-meshheading:6280605-Herpes Simplex, pubmed-meshheading:6280605-Herpesviridae, pubmed-meshheading:6280605-Herpesviridae Infections, pubmed-meshheading:6280605-Herpesvirus 3, Human, pubmed-meshheading:6280605-Herpesvirus 4, Human, pubmed-meshheading:6280605-Humans, pubmed-meshheading:6280605-Intestinal Absorption, pubmed-meshheading:6280605-Keratitis, Dendritic, pubmed-meshheading:6280605-Kidney, pubmed-meshheading:6280605-Kinetics, pubmed-meshheading:6280605-Mice, pubmed-meshheading:6280605-Phosphorylation, pubmed-meshheading:6280605-Rabbits, pubmed-meshheading:6280605-Simplexvirus, pubmed-meshheading:6280605-Time Factors
pubmed:year	1981
pubmed:articleTitle	Acyclovir - a review of the preclinical and early clinical data of a new antiherpes drug.
pubmed:publicationType	Journal Article, Clinical Trial, Review