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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1982-6-14
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pubmed:abstractText |
33 patients with serious gram-negative bacillary infections were treated with cefotaxime. In patients with normal renal function the dose varied between 1.5 to 4 g/day. 17 patients had urinary tract infections, 5 respiratory tract infections, 1 combined urinary tract infection and respiratory tract infection, and 10 miscellaneous infections. 16 patients had septicemia. 25 infections were due to pathogens resistant in vitro to ampicillin, cephalothin, gentamicin and/or tobramycin. 15 infections had failed to respond to ampicillin, cefazolin, gentamicin or tobramycin therapy. 32/33 patients responded favourably to cefotaxime (cure or improvement) but 4 patients developed superinfection with cefotaxime-resistant bacteria. No evidence of nephrotoxicity was observed except for a transient moderate rise in creatinine in one patient.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0036-5548
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57-60
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6280269-Adult,
pubmed-meshheading:6280269-Aged,
pubmed-meshheading:6280269-Anti-Bacterial Agents,
pubmed-meshheading:6280269-Bacterial Infections,
pubmed-meshheading:6280269-Cefotaxime,
pubmed-meshheading:6280269-Drug Resistance, Microbial,
pubmed-meshheading:6280269-Female,
pubmed-meshheading:6280269-Humans,
pubmed-meshheading:6280269-Male,
pubmed-meshheading:6280269-Middle Aged,
pubmed-meshheading:6280269-Respiratory Tract Infections,
pubmed-meshheading:6280269-Urinary Tract Infections
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pubmed:year |
1982
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pubmed:articleTitle |
Cefotaxime therapy of serious infections with multiresistant gram-negative bacilli.
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pubmed:publicationType |
Journal Article
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