Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-4-22
pubmed:abstractText
Hospital isolates of Serratia marcescens able to transfer resistance to up to 11 antibiotics were found to contain conjugative R plasmids. One set of strains harbors only a single R plasmid with a mass of 89 megadaltons (Mdal). This plasmid codes for resistance to nine antibiotics including ampicillin, carbenicillin, cephalothin, streptomycin, kanamycin, gentamicin, tobramycin, sisomycin, and sulfonamides. The 2nd set of strains harbors 2 R plasmids, 1 with a mass of 89 Mdal, the other 57 Mdal. Analysis of progeny from genetic crosses indicates that the larger R plasmid codes for resistance to the same antibiotics as does the 89-Mdal plasmid described above. The 57-Mdal species codes for resistance to ampicillin, carbenicillin, cephalothin, kanamycin, neomycin, and tetracycline. The 89- and 57-Mdal R plasmids appear unrelated by a number of genetic and physical criteria. The 89-Mdal plasmid, but not the 57-Mdal species, is transferable by conjugation to Pseudomonas aeruginosa, and renders this species stably resistant to carbenicillin, streptomycin, kanamycin, gentamicin, tobramycin, and sisomycin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0009-3157
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6-17
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
An R plasmid of Serratia marcescens transferable to Pseudomonas aeruginosa.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.