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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1982-4-22
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pubmed:abstractText |
Hospital isolates of Serratia marcescens able to transfer resistance to up to 11 antibiotics were found to contain conjugative R plasmids. One set of strains harbors only a single R plasmid with a mass of 89 megadaltons (Mdal). This plasmid codes for resistance to nine antibiotics including ampicillin, carbenicillin, cephalothin, streptomycin, kanamycin, gentamicin, tobramycin, sisomycin, and sulfonamides. The 2nd set of strains harbors 2 R plasmids, 1 with a mass of 89 Mdal, the other 57 Mdal. Analysis of progeny from genetic crosses indicates that the larger R plasmid codes for resistance to the same antibiotics as does the 89-Mdal plasmid described above. The 57-Mdal species codes for resistance to ampicillin, carbenicillin, cephalothin, kanamycin, neomycin, and tetracycline. The 89- and 57-Mdal R plasmids appear unrelated by a number of genetic and physical criteria. The 89-Mdal plasmid, but not the 57-Mdal species, is transferable by conjugation to Pseudomonas aeruginosa, and renders this species stably resistant to carbenicillin, streptomycin, kanamycin, gentamicin, tobramycin, and sisomycin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0009-3157
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6-17
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:6276109-Conjugation, Genetic,
pubmed-meshheading:6276109-Culture Media,
pubmed-meshheading:6276109-DNA, Bacterial,
pubmed-meshheading:6276109-DNA Restriction Enzymes,
pubmed-meshheading:6276109-Escherichia coli,
pubmed-meshheading:6276109-Nucleic Acid Hybridization,
pubmed-meshheading:6276109-Pseudomonas aeruginosa,
pubmed-meshheading:6276109-R Factors,
pubmed-meshheading:6276109-Serratia marcescens
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pubmed:year |
1982
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pubmed:articleTitle |
An R plasmid of Serratia marcescens transferable to Pseudomonas aeruginosa.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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