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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4529
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pubmed:dateCreated |
1982-2-25
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pubmed:abstractText |
A specific, acquired chromosomal abnormality (deletion 3p) has been found in at least one chromosome 3 in 100 percent of the metaphases in 12 of 12 cell lines cultured from human small-cell lung cancer tissue and in 2-day tumor culture specimens from three patients. Analysis of the shortest region of overlap shows the deletion to be 3p(14-23). This specific change was not seen in five of five lung cancer cell lines other than small-cell lung cancer or in two lymphoblastoid lines cultured from cells of small-cell lung cancer patients whose tumors had the 3p deletion.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0036-8075
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
8
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pubmed:volume |
215
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
181-2
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:6274023-Carcinoma, Small Cell,
pubmed-meshheading:6274023-Cells, Cultured,
pubmed-meshheading:6274023-Chromosome Deletion,
pubmed-meshheading:6274023-Chromosomes, Human, 1-3,
pubmed-meshheading:6274023-Humans,
pubmed-meshheading:6274023-Karyotyping,
pubmed-meshheading:6274023-Lung Neoplasms
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pubmed:year |
1982
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pubmed:articleTitle |
Specific chromosome defect associated with human small-cell lung cancer; deletion 3p(14-23).
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pubmed:publicationType |
Journal Article
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