pubmed-article:6273817 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6273817 | lifeskim:mentions | umls-concept:C0004595 | lld:lifeskim |
pubmed-article:6273817 | lifeskim:mentions | umls-concept:C0004793 | lld:lifeskim |
pubmed-article:6273817 | lifeskim:mentions | umls-concept:C0035681 | lld:lifeskim |
pubmed-article:6273817 | lifeskim:mentions | umls-concept:C0086860 | lld:lifeskim |
pubmed-article:6273817 | pubmed:issue | 22 | lld:pubmed |
pubmed-article:6273817 | pubmed:dateCreated | 1982-2-12 | lld:pubmed |
pubmed-article:6273817 | pubmed:abstractText | RNA polymerase holoenzymes from many bacterial species share a common promoter recognition specificity since they use the same promoter sites on a variety of templates. These promoters generally include sequences homologous to the average sequences -TTGACA- and -TATAATA-, located -35 and -10 base pairs, respectively, upstream of the transcriptional state site. We have isolated a minor form of B. subtilis RNA polymerase in which the normal sigma subunit (sigma 55) is replaced by a smaller polypeptide (sigma 28) and which is highly specific for a class of promoter sites not used by the sigma 55-holoenzyme. Sequencing of two B. subtilis promoter sites used by the sigma 28-holoenzyme reveals identical sequences at -35 and -10 base pairs from the start site, which are -CTAAA- and -CCGATAT-, respectively. These results confirm that sigma subunit plays a major direct role in promoter sequence recognition, and support a model in which sigma interacts sequentially with -35 and -10 regions, respectively. | lld:pubmed |
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pubmed-article:6273817 | pubmed:language | eng | lld:pubmed |
pubmed-article:6273817 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6273817 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:6273817 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6273817 | pubmed:month | Nov | lld:pubmed |
pubmed-article:6273817 | pubmed:issn | 0305-1048 | lld:pubmed |
pubmed-article:6273817 | pubmed:author | pubmed-author:ChamberlinM... | lld:pubmed |
pubmed-article:6273817 | pubmed:author | pubmed-author:WiggsJ LJL | lld:pubmed |
pubmed-article:6273817 | pubmed:author | pubmed-author:GilmanM ZMZ | lld:pubmed |
pubmed-article:6273817 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6273817 | pubmed:day | 25 | lld:pubmed |
pubmed-article:6273817 | pubmed:volume | 9 | lld:pubmed |
pubmed-article:6273817 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6273817 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6273817 | pubmed:pagination | 5991-6000 | lld:pubmed |
pubmed-article:6273817 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:6273817 | pubmed:year | 1981 | lld:pubmed |
pubmed-article:6273817 | pubmed:articleTitle | Nucleotide sequences of two Bacillus subtilis promoters used by Bacillus subtilis sigma-28 RNA polymerase. | lld:pubmed |
pubmed-article:6273817 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6273817 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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