Linked Life Data

6273465

Source:http://linkedlifedata.com/resource/pubmed/id/6273465

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-2-22
pubmed:abstractText
In anesthetized cats and rats, it is demonstrated that glucose perfusion of the small intestine produces a rapid increase of insulin secretion (IRI) which precedes glycemia variation. This mechanism involves the autonomic nervous system and originates from intestinal glucoreceptors, the existence of which was recently reported. The nervous pathways are described in this study:(1) the afferent pathway is represented by vagal fibers coming from the intestinal glucoreceptors; (2) the efferent pathway involves both sympathetic fibers (splanchnic nerves) and chiefly parasympathetic fibers (vagal nerves). These results are established after surgical suppression of afferent and efferent vagal fibers, and pharmacological exclusion of parasympathetic or sympathetic fibers. The role of this nervous regulation of insulin secretion is discussed with special reference to other already known mechanisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0165-1838
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
351-63
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Nervous regulation of insulin release by the intestinal vagal glucoreceptors.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't