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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
Pt 2
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pubmed:dateCreated |
1981-12-15
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pubmed:abstractText |
The pp60src kinase activity of cells infected with temperature-conditional mutants of Rous sarcoma virus (RSV), which induce only a partial transformation, was compared to the pattern of transformation parameters induced by these mutants. The tsGI251-infected cells were thermosensitive for hexose transport, fibrinolysis, morphological alterations and pp60src kinase activity, but cold-sensitive for loss of growth control. The tsGI253-infected cells were similar to tsGI251-infected cells except that they were only slightly cold-sensitive for loss of growth control and had a very low pp60src kinase activity which was temperature-insensitive. Thus, the pp60src kinase activity measured in vitro with IgG as a substrate did not correlate in a consistent way with any of the measured parameters of transformation.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-1317
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
395-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:6270240-Animals,
pubmed-meshheading:6270240-Avian Sarcoma Viruses,
pubmed-meshheading:6270240-Cell Transformation, Neoplastic,
pubmed-meshheading:6270240-Cell Transformation, Viral,
pubmed-meshheading:6270240-Cells, Cultured,
pubmed-meshheading:6270240-Chick Embryo,
pubmed-meshheading:6270240-Mutation,
pubmed-meshheading:6270240-Oncogene Protein pp60(v-src),
pubmed-meshheading:6270240-Protein Kinases,
pubmed-meshheading:6270240-Temperature,
pubmed-meshheading:6270240-Viral Proteins
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pubmed:year |
1981
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pubmed:articleTitle |
Lack of correlation between pp60src kinase activity and transformation parameters in cells infected with temperature-conditional mutants of Rous sarcoma virus.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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