|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1981-12-22
|
|
pubmed:abstractText |
The effect of short-term caffeine withdrawal on lymphocyte beta-adrenoceptor sensitivity was studied in seven men who had been drinking coffee daily for at least 3 mo before the study. The ratio of cyclic adenosine monophosphate production after in vitro incubation with isoproterenol and a blank was used to assess receptor sensitivity. There was a reduction in sensitivity to isoproterenol but not to prostaglandin E1 3 days after caffeine withdrawal. The mechanism of this effect is not clear, but may represent a biochemical correlate of caffeine-withdrawal syndrome.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0009-9236
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
30
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
436-8
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:6269786-Adrenal Medulla,
pubmed-meshheading:6269786-Adult,
pubmed-meshheading:6269786-Alprostadil,
pubmed-meshheading:6269786-Caffeine,
pubmed-meshheading:6269786-Cyclic AMP,
pubmed-meshheading:6269786-Drug Tolerance,
pubmed-meshheading:6269786-Humans,
pubmed-meshheading:6269786-Isoproterenol,
pubmed-meshheading:6269786-Lymphocytes,
pubmed-meshheading:6269786-Male,
pubmed-meshheading:6269786-Prostaglandins E,
pubmed-meshheading:6269786-Receptors, Adrenergic,
pubmed-meshheading:6269786-Substance Withdrawal Syndrome
|
|
pubmed:year |
1981
|
|
pubmed:articleTitle |
Effects of caffeine withdrawal on isoproterenol-stimulated cyclic adenosine monophosphate.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro
|
